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A Splice-Free Dual-Mode Optical Fiber Biosensor for Sensitive and Temperature-Compensated β-Actin Detection via SPR and MZI Integration
This study presents a novel optical fiber biosensor configured for the concurrent measurement of β-actin (ACTB) and temperature. This device is built upon a single-mode optical fiber platform and uses...
PublicationsAutomatic optimization of flat-field corrections by evaluation and enhancement (EVEN) in multimodal optical microscopy
Uneven illumination affects all images acquired by optical microscopes, especially large, multicolour and nonlinear measurements. Although removal is possible with various algorithms, evaluating raw and...
PublicationsQuantitative optical nanoscopy of mitochondrial-derived vesicles in neurons classifies pre-peroxisomal and clearing organelles
Healthy mitochondria are crucial for maintaining neuronal homeostasis. Their activity depends on a dynamic lipid and protein exchange through fusion, fission, and vesicular trafficking. Studying vesicles...
PublicationsHigh-Resolution Molecular Typing of Vancomycin-Resistant Enterococcus faecium from Romania and Bavaria: Combining Enhanced DNA Microarray and Next Generation Sequencing
Antimicrobial resistance poses a significant challenge for infection control, requiring thedevelopment of accurate and high-throughput diagnostic techniques. We expandedand optimized an existing DNA microarray...
PublicationsUnveiling the molecular dynamics of a nitrile-containing 5-lipoxygenase-activating protein antagonist in primary macrophages through Raman spectroscopy
The nitrile (–CN) functional group is a versatile pharmacophore motif that also serves as an intrinsic, bioorthogonal Raman tag in the silent wavenumber region (1800–2700 cm−1). Here, we exploit...
PublicationsInfluence of light incidence angle and polarization on the refractive index sensitivity of tightly-packed ellipsoidal gold nanoparticle layers
The effect of excitation angle and polarization on the bulk refractive index sensitivity (RIS) of hexagonally-arranged gold nanoparticles is studied through numerical simulations and experiments. Analytical...
PublicationsMetallization and laser sintering of electrical conductor tracks on microporous and temperature-sensitive natural fiber-reinforced plastic
Natural fibre-reinforced polypropylene (NFRP) composites are increasingly used as lightweight, bio-based structural materials in automotive and interior applications. To enable multifunctional components...
PublicationsThe Oral Cavity as a Reservoir for Resistance-and Hypervirulence-Associated Genes of Klebsiella pneumoniae in Hospitalized Patients
Introduction: This study investigated the epidemiology and distribution of carbapenem resistance and virulence genes in Klebsiella pneumoniae strains isolated from the oral cavity of hospitalized patients,...
PublicationsA pathway to versatile, point of care and wearable photonics in the mid-infrared and fingerprint region based on Quantum-cascade lasers and analytical and computational advances [Invited]
This paper aims to propose and discuss a pathway to versatile, portable, and wearable photonics devices in the mid-infrared region. We address the benefits and challenges of midinfrared spectroscopy in...
PublicationsContinuous flow technology for particle focusing in microscopy
Imaging flow cytometry provides access to high-throughput imaging of bioparticles in continuous flow. High-quality images with maximum contrast and optical resolution can be obtained if the particles pass...
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