IR Biospectroscopy

Our research focuses on developing and applying advanced infrared (IR) spectroscopic and imaging methods for the label-free molecular characterization of biological samples, including cells, tissues, microorganisms, and biofluids. We also use a correlative platform integrating IR, Raman, and fluorescence imaging to obtain complementary molecular, structural, and spatial information from the same biological samples.

By combining biospectroscopy with advanced data analysis, we investigate molecular alterations associated with health and disease and establish robust analytical workflows for biomedical and diagnostic applications. Areas of application include, but are not limited to, cancer diagnostics, neurodegenerative diseases, and infectious diseases, with a focus on identifying disease-associated molecular signatures for diagnosis and therapeutic monitoring.

We also investigate the distribution of therapeutic agents in cells and tissues and characterize molecular responses to treatment. A further research focus is proteostasis disruption and nanoplastic-induced protein misfolding in cellular models of neurodegenerative diseases.