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Estimation of spectra sample size for characterizing single cells using micro-Raman spectroscopy
Single-cell micro-Raman spectroscopy has the potential to become a powerful, new cytometric approach for discriminating between cell types and identifying subpopulations of cells based on differences in...
PublicationsHigh vacuum tip-enhanced Raman spectroscope based on a scanning tunneling microscope
In this paper, we present the construction of a high-vacuum tip-enhanced Raman spectroscopy (HV-TERS) system that allows in situ sample preparation and measurement. A detailed description of the prototype...
PublicationsRole of Ce in Yb/Al laser fibers: prevention of photodarkening and thermal effects
We report on detailed investigations of ytterbium (Yb) and aluminum (Al) doped silica fiber and preform samples co-doped with cerium (Ce). The prevention of pump-induced photodarkening (PD) by temporary...
PublicationsDual-telescope multi-channel thermal-infrared radiometer for outer planet fly-by missions
The design of a versatile dual-telescope thermal-infrared radiometer spanning the spectral wavelength range 8 to 200 µm, in five spectral pass bands, for outer planet fly-by missions is described. The...
PublicationsMolecular self-healing mechanisms between C60-fullerene and anthracene unveiled by Raman and two-dimensional correlation spectroscopy
The self-healing polymer P(LMA-co-MeAMMA) cross linked with C60-fullerene has been studied by FT-Raman spectroscopy in combination with two-dimensional (2D) correlation analysis and density functional...
PublicationsQuantification of the fluorescence sensing performance of microstructured optical fibers compared to multi-mode fiber tips
Microstructured optical fibers, particularly those with a suspended-core geometry, have frequently been argued as efficient evanescent-field fluorescence-based sensors. However, to date there has not been...
PublicationsInfluence of Protonation State on the Excited State Dynamics of a Photobiologically Active Ru (II) Dyad
The influence of ligand protonation on the photophysics of a ruthenium (Ru) dyad bearing the 2-(1-pyrenyl)-1H-imidazo[4,5-f][1,10]-phenanthroline (ippy) ligand was investigated by using time-resolved transient...
PublicationsNoise-corrected principal component analysis of fluorescence lifetime imaging data
Fluorescence Lifetime Imaging (FLIM) is an attractive microscopy method in the life sciences, yielding information on the sample otherwise unavailable through intensity-based techniques. A novel Noise-Corrected...
PublicationsNonlinear structured illumination using a fluorescent protein activating at the readout wavelength
Structured illumination microscopy (SIM) is a wide-field technique in fluorescence microscopy that provides fast data acquisition and two-fold resolution improvement beyond the Abbe limit. We observed...
PublicationsOctave-spanning supercontinuum generation in hybrid silver metaphosphate/silica step-index fibers
We reveal the potential of step-index fibers consisting of a metaphosphate glass core and a silica claddingas ultrafast octave-spanning supercontinuum source.The hybrid waveguide was fabricated by pressureassisted...
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