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Synergistic anticancer efect of Pistacia lentiscus essential oils and 5‑Fluorouracil co‑loaded onto biodegradable nanofbers against melanoma and breast cancer
Chemoresistance and severe toxicities represent major drawbacks of chemotherapy. Natural extracts, including the essential oils of Pistacia lentiscus (PLEO), exhibit substantial anticancer and anti-inflammatory...
PublicationsSERS-based detection of the antibiotic ceftriaxone in spiked fresh plasma and microdialysate matrix by using silver-functionalized silicon nanowire substrates
Therapeutic drug monitoring (TDM) is an important tool in precision medicine as it allows estimating pharmacodynamic and pharmacokinetic effects of drugs in clinical settings. An accurate, fast and real-time...
PublicationsLight-Induced Charge Separation in Covalently Linked BODIPY-Quinone-Alkyne Dyads
Visible light-induced charge separation and directional charge transfer are corner stones for artificial photosynthesis and the generation of solar fuels. Here, we report synthetic access to a series of...
PublicationsIn Vivo Near-Infrared Fluorescence Resonance Energy Transfer (NIR-FRET) Imaging of MMP‑2 in ALI/ARDS in LPS-Treated Mice
Matrix metalloproteinases (MMPs) are zinc-dependent proteinases that are capable of cleavage of extracellular matrix (ECM) proteins and enzymes and play an important role in lung dysfunction. Specifically,...
PublicationsNanoencapsulation of general anaesthetics
General anaesthetics are routinely used to sedate patients during prolonged surgeries and administered via intravenous injection and/or inhalation. All anaesthetics have short half-lives, hence the need...
PublicationsA Data Augmentation Methodology to Reduce the Class Imbalance in Histopathology Images
Deep learning techniques have recently yielded remarkable results across various fields. However, the quality of these results depends heavily on the quality and quantity of data used during the training...
PublicationsMMIR: an open-source software for the registration of multimodal histological images
Background: Multimodal histology image registration is a process that transforms into a common coordinate system two or more images obtained from diferent microscopy modalities. The combination of information...
PublicationsIlluminating the Tiny World: A Navigation Guide for Proper Raman Studies on Microorganisms
Raman spectroscopy is an emerging method for the identification of bacteria. Nevertheless, a lot of different parameters need to be considered to establish a reliable database capable of identifying real-world...
PublicationsChargeTransfer Dynamics in Organic–Inorganic Hybrid Heterostructures—Insights by Vibrational-Sum Frequency Generation Spectroscopy
Organic-inorganic heterostructures play a pivotal role in modern electronic and optoelectronic applications including photodetectors and field effect transistors, as well as in solar energy conversion...
PublicationsFindaureus: An open-source application for locating Staphylococcus aureus in fluorescence-labelled infected bone tissue slices
Staphylococcus aureus (S. aureus) is a facultative pathogenic bacterium that can cause infections in various tissue types in humans. Fluorescence imaging techniques have been employed to visualize the...
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