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Capillary-assisted flat-field formation: a platform for advancing nanoparticle tracking analysis in an integrated on-chip optofluidic environment

Here, we present the concept of flat-field capillary-assisted nanoparticle tracking analysis for the characterization of fast diffusing nano-objects. By combining diffusion confinement and spatially invariant...

Coherent Raman spectroscopy: Quo vadis?

Although the potential of Coherent Raman Spectroscopy (CRS) in the area of biomedicine, life sciences and material sciences has been well demonstrated, its wide-spread practical application is still rather...

Identifcation of the optical isomers using laser induced breakdown spectroscopy combined with machine learning

We explore the possibility of extending the LIBS application combined with machine learning for the identification of optical isomers. Three sets of optical isomers, viz., Tryptophan, Alanine, and Leucine,...

Enhancing Control Over Nitric Oxide Photorelease via aMolecular Keypad Lock

Based on Boolean logic, molecular keypad locks secure molecular information, typically with an optical output. Here we investigate a rare example of a molecular keypad lock with a chemical output. To this...

Non-destructive depth reconstruction of Al-Al2Cu layer structure with nanometer resolution using extreme ultraviolet coherence tomography

Non-destructive cross-sectional characterization of materials systems with a resolution in the nanometer range and the ability to allow for time-resolved in-situ studies is of great importance in material...

Generating Airy beams through multimode fibres

Focussing light through a multimode fibre (MMF) is the basis of holographic endoscopes, which currently enable detailed imaging of deep tissue. Achieving high fidelity and purity diffraction-limited foci...

Efficient Intra-Supramolecular Electron Transfer in Zinc Porphyrin-Coumarin Dyads

We report herein the electron transfer process of a novel supramolecular dyads composed of zinc tetraphenylporphyrin (ZnTPP) and zinc 5,15-dinonyl-10,20-diphenylporphyrin (ZnDPP), as electron donors, and...

Experimental validation of numerical point spread function calculation including aberration estimation

Image reconstruction in fluorescence microscopy is highly sensitive to the accuracy of the impulse response, defined as the point spread function (PSF), of the optical system under which the image to reconstruct...

ConsensusPrime—A Bioinformatic Pipeline for Efficient Consensus Primer Design—Detection of Various Resistance and Virulence Factors in MRSA—A Case Study

Background: The effectiveness and reliability of diagnostic tests that detect DNA sequences largely hinge on the quality of the used primers and probes. This importance is especially evident when considering...

Accurate bacterial outbreak tracing with Oxford Nanopore sequencing and reduction of methylation-induced errors