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Computational tissue staining of non-linear multimodal imaging using supervised and unsupervised deep learning

Hematoxylin and Eosin (H&E) staining is the ’gold-standard’ method in histopathology. However, standard H&E staining of high-quality tissue sections requires long sample preparation times including...

FLIM Data Analysis Based on Laguerre Polynomial Decomposition and Machine-Learning

Significance: The potential of fluorescence lifetime imaging microscopy (FLIM) is recently being recognized, especially in biological studies. However, FLIM does not directly measure the lifetimes, rather...

Excitation Energy Dependent Branching Dynamics Determines Photostability of Iron (II) – Mesoionic Carbene Complexes

Photoactive metal complexes containing earthabundant transition metals recently gained interest as photosensitizers in light-driven chemistry. In contrast to the traditionally employed ruthenium or iridium...

Bacterial phenotype dependency from CO2 measured by Raman spectroscopy

In recent years, Raman spectroscopy has become an established method to study medical, biological or environmental samples. Since Raman spectroscopy is a phenotypic method, many parameters can influence...

Long-term sinonasal carriage of Staphylococcus aureus and anti-staphylococcal humoral immune response in patients with chronic rhinosinusitis

The Optofluidic Light Cage – On-Chip Integrated Spectroscopy Using an Antiresonance Hollow Core Waveguide

Emerging applications in spectroscopy-related bioanalytics demand for integrated devices with small geometric footprints and fast response times. While hollow core waveguides principally provide such conditions,...

Material-specific imaging of nanolayers using extreme ultraviolet coherence tomography

Scientific and technological progress depend substantially on the ability to image on the nanoscale. In order to investigate complex, functional, nanoscopic structures like, e.g., semiconductor devices,...

Photophysics of Ruthenium(II) Complexes with thiazole π-extended Dipyridophenazine Ligands

Transition-metal-based donor−acceptor systems can produce long-lived excited charge-transfer states by visible-light irradiation. The novel ruthenium(II) polypyridyl type complexes Ru1 and Ru2 based...

Extruded suspended core fibers from lanthanum-aluminum-silicate glass

We report the use of the extrusion technique at highest temperatures to date (975 °C -1000 °C) for the fabrication of suspended core fibers (SCFs) from glass with molar composition 65 SiO2-20 Al2O3-15...

Observation of direction instability in a fiber ring laser

We report on the observation of a new phenomenon occurring in a fiber ring laser. This phenomenon is about the transition from an initially bidirectional emission of a reciprocal fiber ring laser to a...