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Wide Field Spectral Imaging with Shifted Excitation Raman Difference Spectroscopy Using the Nod and Shuffle Technique

Wide field Raman imaging using the integral field spectroscopy approach was used as a fast, one shot imaging method for the simultaneous collection of all spectra composing a Raman image. For the suppression...

Pulmonary surfactant and drug delivery: Vehiculization, release and targeting of surfactant/Tacrolimus formulations

This work explores the potential for strategizing pulmonary surfactant (PS) for drug delivery over the respiratory air-liquid interface: the interfacial delivery. The efficacy of PS- and interface-assisted...

Shape-Memory Metallopolymers Based on Two Orthogonal Metal-Ligand Interactions

A new shape-memory polymer is presented, in which both the stable phase as well as the switching unit consist of two different metal complexes. Suitable metal ions, which simultaneously form labile complexes...

Lysosome-targeting pH indicator based on peri-fused naphthalene monoimide with superior stability for long term live cell imaging

Lysosomes, the acidic degradation compartments of eukaryotic cells, play an essential role in many physiological processes. Their dysfunction is associated with a number of diseases, which are often related...

Single-atom laser with engineered circuit for population inversion

Surface enhanced Raman spectroscopy-based evaluation of the membrane protein composition of the organohaliderespiring Sulfurospirillum multivorans

Bacteria often employ different respiratory chains that comprise membrane proteins equipped with various cofactors. Monitoring the protein inventory that is present in the cells under a given cultivation...

Fluidity and Lipid Composition of Membranes of Peroxisomes, Mitochondria and the ER From Oleic Acid-Induced Saccharomyces cerevisiae

The maintenance of a fluid lipid bilayer is key for organelle function and cell viability. Given the critical role of lipid compositions in determining membrane properties and organelle identity, it is...

Tailored micro-optical freeform holograms for integrated complex beam shaping

Modern optical measurement technologies such as structured light microscopy or fringe-projection profilometry rely fundamentally on structured illumination of the specimen or probe. Miniaturizing the applied...

Functionalized silicon substrates with stripe-patterned surface near electrostatic forces for the self-organized, stable immobilization of biomolecules

Silicon substrates with stripe-patterned surface-near electrostatic forces (SNEF) were prepared by local implantation of boron ions into n-type silicon wafers and of phosphorus ions into p-type silicon...

Low temperature chemical treatment of graphene films made by double self-assembly process to improve sheet resistance

In this study, a low temperature hydro iodic acid (HI) vapor treatment of the self-assembled graphene films has been developed, and the electrical, optical, structural and morphological properties were...