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Benchmark datasets for 3D MALDI- and DESI-imaging mass spectrometry

Three-dimensional (3D) imaging mass spectrometry (MS) is an analytical chemistry technique for the 3D molecular analysis of a tissue specimen, entire organ, or microbial colonies on an agar plate. 3D-imaging...

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Exploring the Nanoscale: Fifteen Years of Tip-Enhanced Raman Spectroscopy

Spectroscopic methods with high spatial resolution are essential to understand the physical and chemical properties of nanoscale materials including biological and chemical materials. Tip-enhanced Raman...

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Non-linear imaging and characterization of atherosclerotic arterial tissue using combined SHG and FLIM microscopy

Atherosclerosis is one of the leading causes of death in the Western World and its characterization is extremely interesting from the diagnostic point of view. Here, we employed combined SHG-FLIM microscopy...

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Multiscale spectroscopy using a monolithic liquid core waveguide with laterally attached fiber ports

In conventional absorption spectrometers, the range of accessible concentrations of analytes in aqueous solution is significantly limited by the dynamic range of the measurement system. Here we introduce...

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ZrO2 nanoparticles labeled via a native protein corona: detection by fluorescence microscopy and Raman microspectroscopy in rat lungs

ZrO2 nanoparticles are frequently used in composite materials such as dental fillers from where they may be released and inhaled upon polishing and grinding. Since the overall distribution of ZrO2 NP inside...

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Simulating long-distance entanglement in quantum spin chains by superconducting flux qubits

We investigate the performance of superconducting flux qubits for the adiabatic quantum simulation of long-distance entanglement (LDE), namely, a finite ground-state entanglement between the end spins...

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Differentiation of MCF-7 tumor cells from leukocytes and fibroblast cells using epithelial cell adhesion molecule targeted multicore surface-enhanced Raman spectroscopy labels

Identification of tumor and normal cells is a promising application of Raman spectroscopy. The throughput of Raman-assisted cell sorting is limited by low sensitivity. Surface-enhanced Raman spectroscopy...

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How Does Peripheral Functionalization of Ruthenium(II)–Terpyridine Complexes Affect Spatial Charge Redistribution after Photoexcitation at the Franck–Condon Point?

Ruthenium polypyridine-type complexes are extensively used sensitizers to convert solar energy into chemical and/or electrical energy, and they can be tailored through their metal-to-ligand charge-transfer...

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Spectrometer calibration protocol for Raman spectra recorded with different excitation wavelengths

The combination of Raman spectroscopy with chemometrics has gained significant importance within the last years to address a broad variety of biomedical and life science questions. However, the routine...

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