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Monitoring the morphochemistry of laryngeal carcinoma by multimodal imaging
Multimodal nonlinear imaging constitutes a contemporary approach to investigate the morphochemistry of complex samples noninvasively and without administration of external labels. Here we discuss our recent...
PublicationsCharacterization and Application of Innovative Plasmonic Arrays
In order to increase the inherent weak but molecular specific Raman signature the exceptional optical properties of plasmonic nanostructures are used. This technique is termed as surface enhanced Raman...
PublicationsSplitting and switching of microfluid segments in closed channels for chemical operations in the segment-on-demand technology
Basic functional units and a preparation technology have been developed for the investigation of segment operations in larger sequences of droplets. A high reproducibility of segment operations with branched...
PublicationsNoise characterization of highly sensitive SQUID magnetometer systems in unshielded environments
To measure the noise performance of highly sensitive SQUID magnetometers is nearly impossible due to superimposed external noise. Especially in unshielded environment one needs sophisticated methods in...
PublicationsNon-invasive label-free investigation and typing of head and neck cancers by multimodal nonlinear microscopy
Early detection and typing of tumors is pressing matter in clinical research with important impacts for prognosis and successful treatment. Currently, staining is the golden standard in histopathology...
PublicationsDiscrimination of skin diseases using the multimodal imaging approach
Optical microspectroscopic tools reveal great potential for dermatologic diagnostics in the clinical day-to-day routine. To enhance the diagnostic value of individual nonlinear optical imaging modalities...
Publications3D CARS image reconstruction and pattern recognition on SHG images
Nonlinear optical imaging techniques based e.g. on coherent anti-Stokes Raman scattering (CARS) or second-harmonic generation (SHG) show great potential for in-vivo investigations of tissue. While the...
PublicationsSpectroscopic detection of chemotherapeutics and antioxidants
The hand-foot-syndrome presents a severe dermal side-effect of chemotherapeutic cancer treatment. The cause for this side-effect is the elimination of systemically administered chemotherapeutics with the...
PublicationsExtraction of Plasticity Parameters of GaN with High Temperature, In Situ Micro-Compression
Micro-pillar compression has been utilised in a novel elevated temperature technique, in situ in the SEM to characterise the plasticity of Gallium Nitride (GaN) {0001} oriented euhedral prisms grown...
PublicationsAdvances in optical biopsy – correlation of malignancy and cell density of primary brain tumors using Raman microspectroscopic imaging
Raman spectroscopy is a promising tool towards biopsy under vision as it provides label-free image contrast based on intrinsic vibrational spectroscopic fingerprints of the specimen. The current study...
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