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Raman Spectroscopy Can Identify Acute and PersistentBiochemical Changes in Leukocytes From Patients WithCOVID-19 and Non-COVID-19-Associated Sepsis

Sepsis remains a major clinical challenge, often resulting in long-term physiological and immunological disturbances. This study employed high-throughput single-cell Raman spectroscopy to analyze the biochemical...

Publications

Ultrafast Light-Switch Properties of G-Quadruplex Binder: [Ru(phen)2(tpphz-DC3)]4+

Light switch probes, i.e., those that emit only on binding their target, are highly attractive in bioimaging as they provide for outstanding contrast, especially in interrogation of discrete nanoscale...

Publications

Imaging-based quantification of sub-25 nm coking layer on Au by dielectric-loaded plasmonic azimuthally chirped gratings

Noble metals are commonly used in heterogeneous catalysis due to their active catalytic sites. However, carbon layer deposition, or coking, can block these sites and reduce performance, even at thicknesses...

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Characterization of Staphylococcus aureus CC1 and CC1660 of human and equine origin

Background/Objectives: Staphylococcus aureus isolates from humans and horses of the eq-uine-associated clonal complexes (CCs) CC1 and CC1660 were comparatively investi-gated for their genomic relationships....

Publications

Photocatalytic Activity of Ionic Carbon Nitrides is Governedby Cation-Modulated Dark Exciton Dynamics

Ionic polymeric carbon nitrides, poly(heptazine imides) (PHIs), have emerged as promising photocatalysts, yet the relationship between their structure, exciton dynamics, and activity has remained elusive...

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Multimodal Integration Enhances Tissue Image Information Content: A Deep Feature Perspective

Multimodal imaging techniques have the potential to enhance the interpretation of histology by offering additional molecular and structural information beyond that accessible through hematoxylin and eosin...

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The Procaine-Based ProcClusterR Impedes the Second Envelopment Process of Herpes Simplex Virus Type 1

Herpes simplex virus type 1 (HSV-1) has a global prevalence of 64%. Established antiviral drugs, such as acyclovir (ACV), have been successfully used over the past decades. However, due to growing viral...

Publications

High-definition 3D suspended Archimedean spiral with broadband, spatially extended, and single-handed optical chirality enhancement in Vis-NIR range

3D plasmonic structures can provide giant optical chirality (C) in the near field, enabling strong interactions with enantiomers for chiral sensing applications. However, these structures face several...

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Raman spectra comparison: cautions and pitfalls of similarity metrics

Raman spectroscopy detects indirectly vibrations of molecular compounds that can be used as fingerprints of molecules and chemical/biological compounds. This endorses Raman spectroscopy as a powerful tool...

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A comparative study of robustness to noise and interpretability in U-Net-based denoising of Raman spectra

Raman spectroscopy is a valuable analytical technique for molecular characterization, but its practical application is often restricted by low signal-to-noise ratio (SNR), especially at short integration...

Publications

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