6558 Search results for: „“
Super-resolution near-infrared autofluorescence microscopy depicts melanin containing organelles of the retinal pigment epithelium in human donor eyes
Purpose: In the human retinal pigment epithelium (RPE), melanin localizes to melanosomes as well as melanolipofuscin. Changes in the organelles’ volumetric density may have different clinical implications,...
PublicationsDesign of electrochemical aptameric biosensor for the specific and selective detection of chemotherapeutic drugs: Application for paclitaxel and leucovorin
Chemotherapy continues to be a fundamental approach in treating various cancers, with combination therapies frequently improving effectiveness while minimizing toxicity. Recently, the therapeutic potential...
PublicationsBlood biomarker and Raman analysis of leukocytes in the multicenter INTELLIGENCE trials: at the Intensive Care Unit (INTELLIGENCE-1) and the Emergency Department (INTELLIGENCE-2)
Background: Sepsis, defined as life-threatening organ dysfunction caused by a dysregulated host response to infection, goes along with a complex and not yet fully understood host response. Despite many...
PublicationsMultiplexed, rapid phenotypic antibiotics usceptibility testing based on angle-resolved light scattering imaging of microfluidic droplets
Introduction: There is an urgent need for rapid, high-throughput phenotypic antimicrobial susceptibility testing (AST) capable of assessing amicrobial sample’s susceptibility to multiple antibiotics....
PublicationsMixed-mode in-memory computing: towards high-performance logic processing in a memristive crossbar array
In-memory computing is a promising alternative to traditional computer designs, as it helps overcome performance limits caused by the separation of memory and processing units. However, many current approaches...
PublicationsExploring the Influence of Metal Incorporation and Porosity Optimization on the H2O2 Production Efficiency of Templated Poly(Heptazine Imides)
Hydrogen peroxide (H2O2) is a versatile chemical, valued as both a promising energy carrier and a widely used oxidizing agent in disinfection and organic synthesis. The light-driven catalytic oxygen reduction...
PublicationsDeficiency in the Actin Nucleator Cordon Bleu (Cobl) Causes Hypoplastic Enamel in Murine Mandibular Molars
The protein Cordon Bleu (Cobl) belongs to the group of actin nucleators. Through the formation of trimeric actin nuclei, Cobl authorizes the genesis of filamentous actin structures. Cobl has been detected...
PublicationsPoint-of-care SERS-based ML diagnosis of head and neck cancer via cerumen analysis
Early detection of head and neck cancer (HNC) is critical for improving prognosis and survival rates. Many cases are diagnosed at advanced stages due to subtle initial symptoms and the complexity of the...
PublicationsApplication of the Combined QCM-D/LSPR Aptasensor for Penicillin G Detection
Penicillin G (PEN) is a widely used antibiotic for treating microbial infections. However, its extensive use in veterinary medicine can lead to accumulation in animal-derived products, particularly milk...
PublicationsDemystifying in vivo non-resonant Raman spectroscopy of the human retina
Early detection of retinal molecular biomarkers is crucial for addressing the unmet clinical need to prevent irreversible neural tissue damage in ophthalmic and neurodegenerative diseases. Among emerging...
Publications