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Revealing the Chemical Composition of Birch Pollen Grains by Raman Spectroscopic Imaging

The investigation of the biochemical composition of pollen grains is of the utmost interest for several environmental aspects, such as their allergenic potential and their changes in growth conditions...

Comparison of conventional and shifted excitation Raman difference spectroscopy for bacterial identification

Raman spectroscopy is an emerging tool for fast bacterial identification. However, Raman spectroscopy is depending on suitable preprocessing of the spectra, thereby background removal is a decisive step...

aPIE: an angle calibration algorithm for reflection ptychography

Reflection ptychography is a lensfree microscopy technique particularly promising in regions of the electromagnetic spectrum where imaging optics are inefficient or not available. This is the case in tabletop...

Saturated-excitation image scanning microscopy

Image scanning microscopy (ISM) overcomes the trade-off between spatial resolution and signal volume in confocal microscopy by rearranging the signal distribution on a two-dimensional detector array to...

Real-time molecular imaging of near-surface tissue using Raman spectroscopy

The steady progress in medical diagnosis and treatment of diseases largely hinges on the steady development and improvement of modern imaging modalities. Raman spectroscopy has attracted increasing attention...

Attenuation coefficients of selected organic and inorganic solvents in the mid-infrared spectral domain

Knowledge of the light attenuation by a material is essential for any photonic device, while liquids are insufficiently quantified, especially in the mid-infrared range. Here, we present a quantitative...

The Role of Surface Enhanced Raman Scattering for Therapeutic Drug Monitoring of Antimicrobial Agents

The rapid quantification of antimicrobial agents is important for therapeutic drug monitoring (TDM), enabling personalized dosing schemes in critically ill patients. Highly sophisticated TDM technology...

Photonic nanojet of a Gaussian beam illuminated low refractive index microsphere in air: A comprehensive variation of parameters

A photonic nanojet (PNJ) is a narrow beam of concentrated light emerging from the illuminated micro- scattering objects, which has attracted a lot of attention lately. However, so far the variation and...

Raman spectroscopic cellomics for the detection of SARS-CoV-2-associated neutrophil activation after TNF-𝜶 stimulation

IMAGE-IN: Interactive web-based multidimensional 3D visualizer for multimodal microscopy images

Advances in microscopy hardware and storage capabilities lead to increasingly larger multidimensional datasets. The multiple dimensions are commonly associated with space, time, and color channels. Since...