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Radially polarized picosecond MOPA system based on double-clad ytterbium-doped spun tapered fiber with ring-shaped active core

We have demonstrated for the first time, to the best of our knowledge, the successful direct amplification of a cylindrical-vector beams with axially symmetric polarization and doughnut-shaped intensity...

SERS-based detection of 5-S-cysteinyl-dopamine as a novel biomarker of Parkinson’s disease in artificial biofluids†

The early detection of Parkinson’s disease (PD) can significantly improve treatment and quality of life in patients. 5-S-Cysteinyl-dopamine (CDA) is a key metabolite of high relevance for the early detection...

Ultrafast Spectral Tuning of a Fiber Laser for Time-Encoded Multiplex Coherent Raman Scattering Microscopy

Coherent Raman scattering microscopy utilizing bioorthogonal tagging approaches like isotope or alkyne labelling allows for a targeted monitoring of spatial distribution and dynamics of small molecules...

Guided-deconvolution for correlative light and electron microscopy

Correlative light and electron microscopy is a powerful tool to study the internal structure of cells. It combines the mutual benefit of correlating light (LM) and electron (EM) microscopy information....

Enzyme Immobilization Technologies and Industrial Applications

Enzymes play vital roles in diverse industrial sectors and are essential components of many industrial products. Immobilized enzymes possess higher resistance to environmental changes and can be recovered/recycled...

Quantification of biophysical properties of candidalysin, a fungal peptide toxin secreted by C. albicans during invasion

Microfluidic-Generated Seeds for Gold Nanotriangle Synthesis in Three or Two Steps

Nanoparticle synthesis has drawn great attention in the last decades. The study of crystal growth mechanisms and optimization of the existing methods lead to the increasing accessibility of nanomaterials,...

Comparison of bacteria in different metabolic states by micro-Raman spectroscopy

It was shown that several metabolic states of bacteria with various characteristics such as chemical composition participate in the formation of biofilms. To study the connections and differences among...

Using Biological Photophysics to Map the Excited-State Topology of Molecular Photosensitizers for Photodynamic Therapy

In this study, TLD1433 a Ru (II) complex, in human clinical trial in photodynamic therapy (PDT) serves as the benchmark to establish protocols for studying the excited-state dynamics of photosensitizers...

Inside Block Copolymer Micelles—Tracing Interfacial Influences on Crosslinking Efficiency in Nanoscale Confined Spaces

Recently, several studies have demonstrated the excellent capabilities of tip-enhanced Raman spectroscopyfor in-depth investigations of structural properties of matter with unprecedented resolution and...