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Polarized Illumination Coded Structured Illumination Microscopy (picoSIM): Experimental Results
Many microscopy methods achieve special capabilities by recording data, separated in time and subsequently processing this data. Confocal microscopy generates optical sections which look like the object...
Research results | 11.09.2023
Development of a New Antigenbased Microarray Platform for Screening and Detection of Human IgG Antibodies Against SARS-CoV-2
Strategies to contain the current SARS-CoV-2 pandemic rely on molecular and serological testing in addition to vaccination. For any kind of serological test development, the search for the optimal antigen...
Research results | 11.09.2023
Looking Inside F Non-Destructively: Label-Free, Raman-Based Visualization of Intracellular Coxiella burnetii
Intracellular pathogens often exhibit a complex life cycle and can – protected inside of the host cell – cause persistent infections which are difficult to treat. Currently, the characterization of...
Research results | 11.09.2023
Integrated Optically Pumped Magnetometer for Measurements within Earth’s Magnetic Field
Ultrasensitive magnetic field detection is important in a wide range of research areas and applications. Important examples are within biomagnetism, where signals from the human brain or the human (fetal)...
Research results | 11.09.2023
Quantized Current Steps Due to the a.c. Coherent Quantum Phase-Slip Effect
The quantum mechanical tunneling of paired electrons existing in superconductors through an insulating barrier leads to the Josephson effects which enable various applications ranging from medical diagnostics...
Research results | 11.09.2023
Real-time Molecular Imaging of Near-surface Tissue Using Raman Spectroscopy
Raman spectroscopy has shown great potential for clinical in vivo diagnostics by providing the molecular fingerprint of a sample without contact or destruction. However, current fiber optic probe-based...
Research results | 11.09.2023
Trends in Pharmaceutical Analysis and Quality Control by Modern Raman Spectroscopic Techniques
This review paper discusses and explains new developments in Raman-based analytics that are especially important for modern pharmaceutical applications and procedures. The first section introduces Raman...
Research results | 11.09.2023
Nonlinear Optical Signal Generation Mediated by a Plasmonic Azimuthally Chirped Grating
This publication presents an innovative approach to study the plasmonic enhancement effect in nonlinear signal generation (NSG) from gold gratings. Plasmon-enhanced NSG requires specially designed plasmonic...
Research results | 11.09.2023
Targeted Suppression of Peptide Degradation in Ag-Based Surface-Enhanced Raman Spectra by Depletion of Hot Carriers
This paper introduces an efficient suppression method of peptide degradation using iodide demonstrated by a systematic surface-enhanced Raman spectroscopy (SERS) study of a small peptide in aqueous solution....
Research results | 11.09.2023
The Effect of Layer Thickness and Immobilization Chemistry on the Detection of CRP in LSPR Assays
In this work, the potential of localized surface plasmon resonance (LSPR)-based sensing was demonstrated with respect to the detection of a clinically relevant inflammatory biomarker, a C-reactive protein...
Research results | 11.09.2023