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Advanced characterization of block copolymer nanostructures: integrating tip-enhanced Raman scattering and atomic force microscopy for nanoscale chemical, structural, and mechanical insights
Biocompatible and degradable block copolymers offer a versatile alternative to lipids for designing advanced drug delivery systems. However, their self-assembly into hierarchical nanostructures and their...
PublicationsEffect of Organic Binders on the Film Morphology of Hydrogen-Terminated Nanodiamonds Used for Electron Extraction in Organic Solar Cells
Like other carbon nanoparticles, diamond nanoparticles, also known as nanodiamonds (NDs), tend to aggregate when they are dispersed in solution or when they are cast on a substrate. This is mainly due...
PublicationsEfficient delivery of magnolol via polymer and hybrid lipid-polymer particles to human macrophages
Inflammation is a complex host response to combat infections and eliminate pathogens. While essential for tissue repair and homeostasis, prolonged inflammation can lead to chronic disorders. Specialized...
PublicationsPhage–antibiotic synergy restores β-lactam efficacy in MDR Klebsiella quasipneumoniae biofilms and suppresses resistance
Background: Biofilms formed by multidrug-resistant (MDR) Klebsiella spp. present a significant clinical challenge due to elevated antibiotic tolerance. Bacteriophages (phages) represent a promising alternative,...
PublicationsSiamese networks in Raman spectroscopy: Towards a better performance against replicate variability
The power of Raman spectroscopy is largely enhanced by machine learning and chemometrics, which extract and translate the spectral features into high-level biological or clinical knowledge by constructing...
PublicationsIdentification of Natural and Artificial Modifications in DNA at the Nanometer Level
The modification of nucleobases in nucleic acids is a naturally occurring process that can affect various positions of the heteroaromatic ring systems. In addition, by the targeted introduction of an artificial...
PublicationsMetabolite profiling of Bacillus velezensis DM extract linked to the rhizosphere of Datura metel L. and dermatoprotective potential of an isolated glycoglycerolipid
Background: Rhizosphere bacterial metabolites play a pivotal role in drug discovery by producing diverse bioactive compounds with cosmeceuticals and pharmaceuticals applications, offering eco-friendly...
PublicationsA Wearable Microneedle-Integrated Multiplexed Photonic Aptasensor for the Detection of Illicit Drugs in Interstitial Fluid
We present a microneedle-integrated wearable biosensorarray for minimally invasive detection of heroin, cocaine, andmethamphetamine in interstitial fluid (ISF). The platform leveragesaptamer-functionalized...
PublicationsEngineering Interfacial Donor−Acceptor Molecular Cocrystals
Y6 is a high-performance non-fullerene acceptor widely used in organic solar cells. The assembly behavior of Y6 atinterfaces, however, remains mostly unknown and respective in-depth investigations are...
PublicationsA water-soluble copolymer for storage and electron conversion in photocatalytic ondemand hydrogen evolution
Cost- and energy-efficient long-term storage of excess solar energy remains amajor bottleneck in the transition to a sustainable society. Here, we present awater-soluble redox-active copolymer containing...
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