A Study of Docetaxel induced effects in MCF-7 Cells by means of Raman microspectroscopy

in: Analytical and Bioanalytical Chemistry (2012)
Putsche, Melanie; Hartmann, Katharina; Bocklitz, Thomas W.; Rösch, Petra; Popp, Jürgen; Niendorf, Axel; Pachmann, Katharina
Chemotherapies feature a low success rate of about 25%, and therefore, the choice of the most effective cytostatic drug for the individual patient and monitoring the efficiency of an ongoing chemotherapy are important steps towards personalized therapy. Thereby, an objective method able to differentiate between treated and untreated cancer cells would be essential. In this study, we provide molecular insights into Docetaxel-induced effects in MCF-7 cells, as a model system for adenocarcinoma, by means of Raman

DOI: Array

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