Infrared Spectroscopy at Biological Interfaces

Our Research

We develop infrared-based spectroscopic and microscopic methods to visualize molecular structures and processes in biological and biohybrid systems – label-free and with chemical specificity.

Our research focuses on biological interfaces, such as cell membranes and tissue surfaces. These interfaces play a crucial role in many biological and medical processes but are difficult to investigate using conventional methods. Using linear and nonlinear infrared spectroscopy and microscopy, we investigate how molecules are structured and oriented at such interfaces, how they change, and how they interact with one another.

Our research ranges from biological membranes and biomacromolecules to bacterial biofilms and biohybrid and functionalized materials. The insights gained are intended to contribute to a better understanding of molecular structure–function relationships and to provide new foundations for biophotonic analytical methods, biosensors, and future diagnostic applications.

Another focus is on data science and AI-based methods. They help us analyze and model complex infrared data, interpret molecular fingerprints, and integrate information from different spectroscopic and imaging techniques.

Work Groups 

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