The research department focuses on researching, developing and implementing innovative optical/photonic methods and tools for multiscale spectroscopy and multimodal imaging together with particle- and chip-based molecular point-of-care concepts for analytics, diagnostics and therapy in the fields of medicine, life and environmental sciences, quality and process analytics as well as pharmacy. The implementation of novel fiber concepts for spectroscopy and imaging as well as fiber-assisted sensor technology and the use of surface-enhanced Raman and IR detection techniques to increase the sensitivity of spectroscopic methods complete the research profile of the department. In general, the research department pursues the goal of covering the entire analysis measurement chain, whereby sample preparation methods that can be used locally and independently of the laboratory are investigated and implemented in the entire workflow. Statistical, chemometric and image-evaluating methods as well as machine learning are researched and used to evaluate the data obtained.
The search for new molecular and functional contrast mechanisms, their implementation in innovative spectral-optical methods and the instrumentation based on them are a central challenge. Here, two complementary approaches are pursued: While a top-down approach based on physical measurement methods can be used to increase specificity and sensitivity, the research, development, and integration of innovative markers and labels represents a bottom-up approach to chemical contrast.
The research, development and implementation of innovative technologies and processes are particularly aimed for: