For his research project LIFEGATE, Tomáš Čižmár received the Consolidator Grant funded by the European Research Council (ERC) - an award for excellent scientists. Čižmár initially wants to investigate the processes of light propagation in multimode fibers in more detail. The €2 million project aims to explore new, ultrathin instruments for endoscopy that exceed the performance of previous devices by several orders of magnitude. This is expected to pave the way for high-resolution in vivo imaging inside very delicate tissues. A transdisciplinary approach will extend the fundamental and technological limits of the principle used, holographic control of light conduction in multimodal fibers. In the high-risk research project, using advanced analytical and numerical modeling as well as further development of experimental methods, a powerful platform for fast and efficient reconstruction of randomized images from rigid as well as flexible single-fiber endoscopes will be created. The platform thus opens a new minimally invasive window to study the fundamental processes of functional connectivity between neurons and the onset of neurological diseases such as Alzheimer's at the subcellular level.

The project is funded by EU Horizon 2020 grant number 724530, ERC-2016-COG - ERC Consolidator Grant and co-funded by the EU-H2020 ERC project management agency. 

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