Early Detection of Inflammatory Responses

Inflammatory responses are central defense mechanisms of the body. However, many of the underlying processes at the molecular level remain insufficiently understood. In particular, early cellular alterations are often only partially accessible with established analytical methods.

InflamoDetect investigates these early molecular events using adapted optical microscopy techniques in combination with spectroscopic approaches, supported by validated cell and organoid models. The aim is to identify, temporally resolve, and systematically analyze characteristic molecular signatures of inflammatory processes.

Building on this foundation, technical methods are being developed and evaluated to enable faster and more precise diagnosis, classification, and analysis of inflammatory responses. The resulting data will contribute to a better understanding of cellular damage mechanisms and may support earlier and more targeted interventions, for example in the context of severe systemic reactions such as sepsis.

Funded by the Free State of Thuringia through the European Social Fund Plus (Grant number: 2025 FGR 0069).