Strong persistent luminescence (PeL) from silica bodies was obtained, for the first time, by sintering silica powder mixed with PeL SrAl2O4:Eu2+,Dy3+ microparticles (MPs). We show that it is not possible to prepare transparent PeL silica glass due to the decomposition of the MPs, which occurs already at 1450 oC. The MPs decomposition was associated with the precipitation of Sr3Al10SiO20 phase when sintering up to 1650 oC and of SrAl2Si2O8 when sintering between 1650 and 1750 oC. Cristobalite was found to also precipitate when sintering for 10 min but has no impact on the PeL of the bodies.