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Comparative genomics and DNA array-based genotyping of pandemic Staphylococcus aureus strains encoding Panton-Valentine leukocidin
Within the last few years, methicillin-resistant Staphylococcus aureus (MRSA) strains encoding Panton-Valentine leukocidin (PVL) have emerged and spread worldwide. This epidemic can be attributed to a...
PublikationenRapid genotyping of methicillin-resistant Staphylococcus aureus (MRSA) isolates using miniaturised oligonucleotide arrays
This study evaluated a DNA oligonucleotide array that recognised 38 different Staphylococcus aureus targets, including all relevant resistance determinants and some toxins and species-specific controls....
PublikationenDNA microarray-based genotyping of methicillin-resistant Staphylococcus aureus strains from Eastern Saxony
A diagnostic microarray was used to characterise a collection of methicillin-resistant Staphylococcus aureus (MRSA) isolates from hospitals in the German region of Eastern Saxony. The most abundant epidemic...
PublikationenComplex patterns in a trans-cooperatively coupled DNA amplification system
An isothermal biochemical in vitro amplification system with two trans-cooperatively coupled amplifying DNA molecules was investigated as a simple reaction-diffusion system. In a model of the recently...
PublikationenIn vitro evolution of molecular cooperation in CATCH, a cooperatively coupled amplification system
Background: One of the key issues in the investigation of evolution is how complex systems evolved from simple chemical replicators. Theoretical work proposed several models in which complex replicating...
PublikationenDNA-Microarray-based Genotyping of Clostridium difficile
Background: Clostridium difficile can cause antibiotic-associated diarrhea and a possibility of outbreaks in hospital settings warrants molecular typing. A microarray was designed that included toxin genes...
PublikationenCharacterisation of MRSA strains isolated from patients in a hospital in Riyadh, Kingdom of Saudi Arabia
Background: Methicillin-resistant Staphylococcus aureus (MRSA) is spreading worldwide and poses a serious public health problem, being present in hospital settings and communities. However, from the Middle...
PublikationenEvolution and diversity of community-associated methicillin-resistant Staphylococcus aureus in a geographical region
Background: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) was first reported in remote regions of Western Australia and is now the predominant MRSA isolated in the state. The...
PublikationenGenotyping of Chlamydophila psittaci using a new DNA microarray assay based on sequence analysis of ompA genes
Background: The currently used genotyping system for the avian zoonotic pathogen Chlamydophila (C.) psittaci has evolved from serology and is based on ompA sequence variations. It includes seven avian...
PublikationenAn alternative method to amplify RNA without loss of signal conservation for expression analysis with a proteinase DNA microarray in the ArrayTube (R) format
Background: Recent developments in DNA microarray technology led to a variety of open and closed devices and systems including high and low density microarrays for high-throughput screening applications...
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