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Large-scale assembly and pattern transfer of SERS-active nanoparticles for application in drug monitoring of methotrexate in blood serum
Self-assembly of plasmonic gold nanoparticles (AuNPs) in periodic arrays with nanometric gaps results in the optimization of near- and far-field effects, which provides excellent surface-enhanced Raman...
Publikationen | 31.03.2023Multifocal hyperspectral Raman imaging setup for multi-well plates
High-throughput screening has become widespread in drug discovery. This increases the need for efficient, parallelized spectral imaging techniques. However, current designs focus on microplate readers...
Publikationen | 31.03.2023Step-by-step : A microfluidic (PDMS) staircase device for size sorting microparticles down to 25 μm using a 3D-printed mold
Microparticles are ubiquitous and span from living matter to microplastics to inorganic materials. Their detection and identification must be more accessible and time efficient. Microfluidic devices can...
Publikationen | 31.03.2023Enhancing on/off ratio of a dielectric-loaded plasmonic logic gate with an amplitude modulator
Plasmonic waveguides allow focusing, guiding, and manipulating light at the nanoscale and promise the miniaturization of functional optical nanocircuits. Dielectric-loaded plasmonic (DLP) waveguides and...
Publikationen | 28.03.2023Opportunities of optical and spectral technologies in intraoperative histopathology
Modern optical and spectral technologies represent powerful approaches for a molecular characterization of tissues enabling delineating pathological tissues but also a label-free grading and staging of...
Publikationen | 27.03.2023Radially polarized picosecond MOPA system based on double-clad ytterbium-doped spun tapered fiber with ring-shaped active core
We have demonstrated for the first time, to the best of our knowledge, the successful direct amplification of a cylindrical-vector beams with axially symmetric polarization and doughnut-shaped intensity...
Publikationen | 27.03.2023SERS-based detection of 5-S-cysteinyl-dopamine as a novel biomarker of Parkinson’s disease in artificial biofluids†
The early detection of Parkinson’s disease (PD) can significantly improve treatment and quality of life in patients. 5-S-Cysteinyl-dopamine (CDA) is a key metabolite of high relevance for the early detection...
Publikationen | 21.03.2023Ultrafast Spectral Tuning of a Fiber Laser for Time-Encoded Multiplex Coherent Raman Scattering Microscopy
Coherent Raman scattering microscopy utilizing bioorthogonal tagging approaches like isotope or alkyne labelling allows for a targeted monitoring of spatial distribution and dynamics of small molecules...
Publikationen | 15.03.2023Guided-deconvolution for correlative light and electron microscopy
Correlative light and electron microscopy is a powerful tool to study the internal structure of cells. It combines the mutual benefit of correlating light (LM) and electron (EM) microscopy information....
Publikationen | 14.03.2023Enzyme Immobilization Technologies and Industrial Applications
Enzymes play vital roles in diverse industrial sectors and are essential components of many industrial products. Immobilized enzymes possess higher resistance to environmental changes and can be recovered/recycled...
Publikationen | 07.03.2023