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Exploring the evolution and epidemiology of the European CC1-MRSA-IV: tracking a multidrug-resistant community-associated methicillin-resistant Staphylococcus aureus clone

Is electron ping-pong limiting the catalytic hydrogen evolution activity in covalent photosensitizer-polyoxometalate dyads?

Understanding the limitations of catalytic processes enables the design of optimized catalysts. Here, femtosecond transient absorption spectroelectrochemistry is used to explore the photophysics of polyoxometalate-based...

Detection and Differentiation of Bacterial and Fungal Infection of Neutrophils from Peripheral Blood Using Raman Spectroscopy

Neutrophils are important cells of the innate immune system and the major leukocyte subpopulation in blood. They are responsible for recognizing and neutralizing invading pathogens, such as bacteria or...

Dithiafulvenyl-equipped Ru(II) bis-terpyridine complexes – Synthesis, photophysical and electrochemical properties

Dithiafulvalenes (DTFs) represent an important class of organic dyes known for their redox-activity and ability to oxidatively dimerize into tetrathiafulvalene vinylogues (TTFVs). These systems, in turn,...

Radiometric and angular calibration tests for the MEDA-TIRS radiometer onboard NASA’s Mars 2020 mission

This article describes a comprehensive testing method for the radiometric and angular calibration of the Thermal InfraRed Sensor (TIRS) onboard NASA’s Mars 2020 mission. First, details of the TIRS optomechanical...

FLIm-Guided Raman Imaging to Study Cross-Linking and Calcification of Bovine Pericardium

Bovine pericardium (BP) is a vascular biomaterial used in cardiovascular surgery that is typically cross-linked for masking antigenicity and enhance stability. There is a need for biochemical evaluation...

Multiple distinct outbreaks of Panton-Valentine leukocidin (PVL)-positive community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in Ireland investigated by whole-genome sequencing

Background: Panton-Valentine leukocidin (PVL)-positive community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) are increasingly associated with infection outbreaks. Aim: To investigate...

A miRNA biosensor based on localized surface plasmon resonance enhanced by surface-bound hybridization chain reaction

The dysregulation of the concentration of individual circulating microRNAs or small sets of them has been recognized as a marker of disease. For example, an increase of the concentration of circulating...

Autofluorescent Granules of the Human Retinal Pigment Epithelium: Phenotypes, Intracellular Distribution, and Age-Related Topography

PURPOSE. The human retinal pigment epithelium (RPE) accumulates granules significant for autofluorescence imaging. Knowledge of intracellular accumulation and distribution is limited. Using high-resolution...

Deep learning as phase retrieval tool for CARS spectra

Finding efficient and reliable methods for the extraction of the phase in optical measurements is challenging and has been widely investigated. Although sophisticated optical settings, e.g. holography,...