6814 Suchergebnisse für: „“

Cytosolic innate immune pathway activation by Gram-positive bacteria during sepsis

Organ damage and mortality in sepsis have been attributed to deleterious and inappropriate host response during infection. Over the course of sepsis a systemic hyper inflammatory response as well as innate...

Use of meat juice and blood serum with a miniaturised protein microarray assay to develop a multi-parameter IgG screening test with high sample throughput potential for slaughtering pigs

Background: Serological screening of pig herds at the abattoir is considered a potential tool to improve meat inspection procedures and herd health management. Therefore, we previously reported the feasibility...

Rapid antimicrobial susceptibility testing (AST) using Raman spectroscopy combined with a multiwell-dielectrophoresis chip

Introduction: Over the past yearsmulti-resistant pathogens have become an acute healthcare problem worldwide, which also critically affects sepsis patients. In order to initiate appropriate antibiotic...

Cholesterol supplementation protects hepatocytes against the cholesterol-dependent pore-forming toxin pneumolysin

Introduction: Pneumolysin (PLY) is a major virulence factor of Streptococcus pneumonia and crucial for the pathogenesis of invasive pneumococcal disease and sepsis following community-acquired pneumonia...

Photonic imaging can reveal localization of bacteria during hematogenous osteomyelitis

Introduction: One possible long-term consequence of sepsis is hematogenous osteomyelitis, i.e. the spread of bacteria from the blood stream to the bone. The clinical picture of this disease is swelling...

Mechanical properties of plasma membrane vesicles correlate with lipid order, viscosity and cell density

Regulation of plasma membrane curvature and composition governs essential cellular processes. The material property of bending rigidity describes the energetic cost of membrane deformations and depends...

Block Copolymers Featuring Highly Photostable Photoacids Based on Vinylaphthol: Synthesis and Self-Assembly

Polymeric Photoacids based on Naphthols – Design Criteria, Photostability, and Light-Mediated Release

The implementation of photoswitches within polymers offers an exciting toolbox in the design of light-responsive materials. We introduce a range of water-soluble copolymers featuring naphthol-based chromophores...

Block Copolymers Featuring Highly Photostable Photoacids Based on Vinylnaphthol: Synthesis and Self-Assembly

The synthesis of well-defined and light-responsive block copolymers containing vinyl naphthol (VN) as photoacidic comonomer via RAFT is presented. This specific photoacid has been identified in earlier...

Impact of deuteration on the ultrafast nonlinear optical response of toluene and nitrobenzene

Nonlinear pulse propagation inside highly nonlinear media requires accurate knowledge on the temporal response function of the materials used particular in the case of liquids. Here we study the impact...