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The Hollow Core Light Cage: Trapping Light Behind Bars
Optical waveguides represent the key element of integrated planar photonic circuitry having revolutionized many fields of photonics ranging from telecommunications, edicine, environmental science and...
PublikationenSuper-resolution microscopy demystified
Super-resolution microscopy (SRM) bypasses the diffraction limit, a physical barrier that restricts the optical resolution to roughly 250 nm and was previously thought to be impenetrable. SRM techniques...
PublikationenOptical Fiber Probe Viscometer based on Hollow Capillary Tube
Viscosity measurements of a solution are crucial for many processes involving fluid flows. The current optical fiber viscometers are complex and, in some cases, provide indirect measurements of viscosity...
PublikationenMolecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions
Antibodies against the Membrane-Proximal External Region (MPER) of the Env gp41 subunit neutralize HIV-1 with exceptional breadth and potency. Due to the lack of knowledge on the MPER native structure...
PublikationenRaman-based cw supercontinuum generation in a fiber ring laser with low-output coupling
We demonstrate a new technique to generate a continuous-wave supercontinuum based on the stimulated Raman effect in an Yb-based ring laser configuration. Continuously pumping this ring cavity with a maximum...
PublikationenESBL colonization and acquisition in a hospital population: The molecular epidemiology and transmission of resistance genes
A prospective cohort study (German Clinical Trial Registry, No. 00005273) was performed to determine pre-admission colonization rates, hospital acquisition risk factors, subsequent infection rates and...
PublikationenResonance Raman Spectro-Electrochemistry to Illuminate Photo-Induced Molecular Reaction Pathways
Electron transfer reactions play a key role for artificial solar energy conversion, however, the underlying reaction mechanisms and the interplay with the molecular structure are still poorly understood...
PublikationenRaman spectroscopy reveals LPS-induced changes of biomolecular composition in monocytic THP-1 cells in a label-free manner
The human innate immune system is able to recognize pathogen-associated molecular patterns like lipopolysaccharides (LPS) leading to the activation of signal cascades and the release of different cytokines....
PublikationenRaman spectroscopy follows time-dependent changes in T lymphocytes isolated from spleen of endotoxemic mice
T lymphocytes (T cells) are highly specialized members of the adaptive immune system and hold the key to the understanding the hosts’ response toward invading pathogen or pathogen-associated molecular...
PublikationenBiomedical imaging by means of linear and non-linear Raman microspectroscopy
Biomedical imaging by means of nonlinear Raman microspectroscopy offers novel approaches towards individualized decisions on therapy routines as diagnosis is possible on the chemical composition of tissue...
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