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Lipofuscin Redistribution and Loss Accompanied by Cytoskeletal Stress in Retinal Pigment Epithelium of Eyes With Age-Related Macular Degeneration

Purpose: Lipofuscin (LF) and melanolipofuscin (MLF) of the retinal pigment epithelium (RPE) are the principal source of autofluorescence (AF) signals in clinical fundus-AF imaging. Few details about how...

Simultaneous measurement of strain and temperature based on clover microstructured fiber loop mirror

In this work, two all-fiber loop mirrors using a clover microstructured fiber for the simultaneous measurement of temperature and strain are presented. The sensing heads are formed by a short piece of...

Combining multiset resolution and segmentation for hyperspectral image analysis of biological tissues

Hyperspectral images can provide useful biochemical information about tissue samples. Often, Fourier transform infrared (FT-IR) images have been used to distinguish different tissue elements and changes...

Fiber-enhanced Raman multi-gas spectroscopy: what is the potential of its application to breath analysis?

Enhanced Raman Spectroscopy (CERS and FERS)

Cell identification using Raman spectroscopy in combination with optical trapping

Cell identification by Raman spectroscopy has evolved to be an attractive complement to established optical techniques. Raman activated cell sorting (RACS) offers prospects to complement the widely applied...

Microfluidically supported biochip design for culture of endothelial cell layers with improved perfusion conditions

Hemodynamic forces generated by the blood flow are of central importance for the function of endothelial cells (ECs), which form a biologically active cellular monolayer in blood vessels and serve as a...

Towards TiO2-Ag porous nanocomposites based SERS sensors for chemical pollutant detection

Since the TiO2 environmental friendly character and the affinity of a large variety of molecules to bind to the silver surfaces are well-known, novel porous nanoarchitectures based on TiO2 aerogel and...

Suspended Ring-Core Photonic Crystal Fiber Gas Sensor With High Sensitivity and Fast Response

We demonstrate design and fabrication of an in-line evanescent field gas sensor based on a novel suspended ring core photonic crystal fiber (PCF) to further overcome limitations in sensing capability....

Origins of modal loss of antiresonant hollow-core optical fibers in the ultraviolet

Recently, a novel antiresonant hollow core fiber was introduced having promising UV guiding properties. Accompanying simulations predicted ten times lower loss than observed experimentally. Increasing...