6816 Suchergebnisse für: „“

Raman signatures of single point defects in hexagonal boron nitride quantum emitters

Point defects in solid-state quantum systems are vital for enabling single-photon emission at specific wavelengths, making their precise identification essential for advancing applications in quantum technologies....

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Generation of an Induced Pluripotent Stem Cell-Derived Alveolar Type II In Vitro Model to Study Influenza A Virus Infection and Drug Treatments

Influenza viruses (IVs) represent a significant global health issue, capable of causing seasonal epidemics and occasional pandemics with substantial morbidity and mortality. The emergence of viral resistance...

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A Splice-Free Dual-Mode Optical Fiber Biosensor for Sensitive and Temperature-Compensated β-Actin Detection via SPR and MZI Integration

This study presents a novel optical fiber biosensor configured for the concurrent measurement of β-actin (ACTB) and temperature. This device is built upon a single-mode optical fiber platform and uses...

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Automatic optimization of flat-field corrections by evaluation and enhancement (EVEN) in multimodal optical microscopy

Uneven illumination affects all images acquired by optical microscopes, especially large, multicolour and nonlinear measurements. Although removal is possible with various algorithms, evaluating raw and...

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Quantitative optical nanoscopy of mitochondrial-derived vesicles in neurons classifies pre-peroxisomal and clearing organelles

Healthy mitochondria are crucial for maintaining neuronal homeostasis. Their activity depends on a dynamic lipid and protein exchange through fusion, fission, and vesicular trafficking. Studying vesicles...

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High-Resolution Molecular Typing of Vancomycin-Resistant Enterococcus faecium from Romania and Bavaria: Combining Enhanced DNA Microarray and Next Generation Sequencing

Antimicrobial resistance poses a significant challenge for infection control, requiring thedevelopment of accurate and high-throughput diagnostic techniques. We expandedand optimized an existing DNA microarray...

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Unveiling the molecular dynamics of a nitrile-containing 5-lipoxygenase-activating protein antagonist in primary macrophages through Raman spectroscopy

The nitrile (CN) functional group is a versatile pharmacophore motif that also serves as an intrinsic, bioorthogonal Raman tag in the silent wavenumber region (18002700 cm1). Here, we exploit...

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Influence of light incidence angle and polarization on the refractive index sensitivity of tightly-packed ellipsoidal gold nanoparticle layers

The effect of excitation angle and polarization on the bulk refractive index sensitivity (RIS) of hexagonally-arranged gold nanoparticles is studied through numerical simulations and experiments. Analytical...

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Metallization and laser sintering of electrical conductor tracks on microporous and temperature-sensitive natural fiber-reinforced plastic

Natural fibre-reinforced polypropylene (NFRP) composites are increasingly used as lightweight, bio-based structural materials in automotive and interior applications. To enable multifunctional components...

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The Oral Cavity as a Reservoir for Resistance-and Hypervirulence-Associated Genes of Klebsiella pneumoniae in Hospitalized Patients

Introduction: This study investigated the epidemiology and distribution of carbapenem resistance and virulence genes in Klebsiella pneumoniae strains isolated from the oral cavity of hospitalized patients,...

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