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Photocatalytic Activity of Ionic Carbon Nitrides is Governed by Cation-Modulated Dark Exciton Dynamics
Ionic polymeric carbon nitrides, poly(heptazine imides) (PHIs), have emerged as promising photocatalysts, yet the relationship between their structure, exciton dynamics, and activity has remained elusive...
PublikationenAutomatic colocalization of high resolution MALDI MSI and Raman imaging applied to cardiac tissue of Fabry disease mouse models
Understanding early molecular changes in biological tissues is crucial for diagnosing pathological and genetic diseases and for elucidating their underlying mechanisms. However, localized molecular alterations...
PublikationenSpectral STED microscopy improves spectral sensitivity with polarity-sensitive probes and enables correlative measurements of membrane order and anomalous lipid diffusion
Molecular plasma membrane organization and dynamics play an important role in cellular signalling. Advances in our understanding of the nanoscale architecture of the plasma membrane heavily rely on the...
PublikationenParameter Optimization for Iterative MINFLUX Microscopy enabled Single Particle Tracking
MINFLUX fluorescence microscopy is a recently introduced super-resolution approach for studying cellular structures and their dynamics with highest detail. Iterative MINFLUX (iMFX) performs Single Particle...
PublikationenEvent-triggered MINFLUX microscopy: smart microscopy to catch and follow rare events
MINFLUX microscopy is a powerful microscopy method allowing for the characterization of molecular organization and dynamics with single nanometer spatial resolution and sub-hundred microseconds temporal...
PublikationenLight-driven hydrogen evolution reactivity of molecular thio-oxomolybdate catalysts
Molybdenum sulfides are widely used noble metal-free hydrogen evolution reaction (HER) catalysts. Their molecular analogues, so-called thiomolybdates, have been developed as viable minimal models to study...
PublikationenCCB79 is a primate-specific cilium initiation factor essential to maintain neural progenitor diversity in developing brain tissue
Identifying the genes that regulate the accurate spatiotemporal diversity of neural progenitor cells (NPCs) helps to understand the mechanisms of human neocortex expansion. In primate brains, an additional...
PublikationenNanTex enables computational multiplexing and phenotyping of organelles across super-resolution modalities
Super-resolution microscopy (SRM) enables nanoscale visualization of cellular organelles but remains constrained by spectral overlap, labeling requirements, and temporal offsets in multicolor imaging....
PublikationenChromatix: a differentiable, GPU-accelerated wave-optics library
Modern microscopy methods incorporate computational modeling of optical systems as an integral part of the imaging process, either to solve inverse problems or enable optimization of the optical system...
PublikationenAbsolute Membrane Potential Recording with ASAP-Type Genetically Encoded Voltage Indicators Using Fluorescence Lifetime Imaging
The electrical membrane voltage (Vm) characterizes the functional state of biological cells, thus requiring precise, non-invasive Vm-sensing techniques. While voltage-dependent fluorescence intensity...
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