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- Quantitative SERS studies by combining LOC-SERS with the standard addition method
Quantitative SERS studies by combining LOC-SERS with the standard addition method
in: Analytical and Bioanalytical Chemistry (2015)
Here, we report on a proof-of-concept study highlighting a new approach for quantitative surface enhanced Raman spectroscopy (SERS) measurements. This has been achieved by implementing the standard addition method (SAM) within a lab-on-a-chip (LOC) system. The approach has been successfully tested to quantify congo red as a model analyte even in the presence of the chemically related mole- cule methyl red. Thus, the developed concept demonstrates its potential to quantify analytes via SERS in the presence of other SERS active molecules.