Nanobiophotonik

Sensors based on the localized surface plasmon resonance (LSPR) effect are known as sensitive methods for refractive index measurements or for detection of specific binding reactions in biosensing due to a variation in layer thickness. Fiber based arrangements are able to perform such measurements with very small analyte volumina. A generalization of this concept for a multiplexed measurement of different biomolecules in a single fiber could be an attractive approach. We discuss the possibility of selectively sensitizing the inner surfaces of a suspended core fiber with two different metallic nanoparticle types in monolayers for such multiplexed measurements.