The research of the group "Fiber Spectroscopic Sensors" focuses on the development of miniaturized, fiber- and cavity-based Raman sensors and their interdisciplinary application in environmental, pharmaceutical and biomedical areas.
We exploit the high chemical selectivity of Raman spectroscopy for the identification and quantification of biogenic gases, drugs and biomolecules in complex samples. The development of novel micro-structured hollow-core fibers (e.g. for guidance in the deep-UV) and optical cavities provides us high signal enhancements. Thus, it enables us to monitor minimal sample concentrations onsite in small sample volumes with high selectivity and sensitivity.
Our research regarding tailor-made optical sensors is closely connected to the interdisciplinary application in various environmental and life science topics. This interdisciplinary research is done in close cooperation with partners from CRC AquaDiva and the Jena university hospital.
- Fiber enhanced Raman spectroscopy (FERS)
- Design of novel hollow core fiber for ultraviolet guidance
- Cavity enhanced Raman spectroscopy (CERS)
- Raman spectroscopic gas sensing
- Fiber array based Raman imaging
Addressed interdisciplinary applications
- Characterization of metabolism changes of plants due to climate relevant environmental changes, such as the drought-resistance of different types of trees
- Analysis of microbial gas exchange in mesocosms and of onsite soil gas depth profiles
- Research regarding element cycles (e.g. nitrogen cycle – denitrification, nitrogen fixation)
- Analysis of microbial degradation of pollutants in soil
- Analysis of gaseous and volatile disease markers in breath for non-invasive early stage disease diagnosis
- Highly sensitive and selective analysis of pharmaceutical drugs in aqueous environments (e.g. in body fluids)
- Analysis of molecular interactions between active agents and their biological targets, with focus on antimalarial drugs