Master Thesis “Monitoring dyes in cell membrane models”

In the working groups Organic Thin Films and Interfaces at Leibniz Institute of Photonic Technology (Leibniz-IPHT) and Superresolution Microscopy at the Institute for Applied Optics and Biophysics (FSU-Jena) now offers the possibility for a

Master Thesis

“Monitoring dyes in cell membrane models”

In pharmaceutics and medicine, cell membrane models are essential for the study of pharma­co­logical processes. The function of cell membranes depends on their fluidity, which can be controlled by additives and the manufacturing parameters. Within the scope of the master thesis, systematically varied cell membranes will be prepared and the influence of the manu­fac­turing parameters and cell membrane composition on the fluidity of the cell membrane models will be investigated by means of high-resolution fluorescence microscopy.

 

Your tasks:

  • Familiarization with the Langmuir-Blodgett (LB) technique and high-resolution microscopy
  • Preparation of LB membranes from systematically varied lipid-dye mixtures
  • Characterization of the membrane
    • Microscopic (optical, scanning electron microscopy) techniques
    • UV-vis absorption spectroscopy
    • Advanced fluorescence microscopy techniques

Further information:

If you are interested in these topics, please apply directly to PD Dr. habil. Martin Presselt (martin.presselt@leibniz-ipht.de) or Prof. Dr. Christian Eggeling (christian.eggeling@uni-jena.de), or simply apply via our job portal (https://www.leibniz-ipht.de/en/institute/career/job-portal) by clicking on the “apply” button:

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