In the joint project, a combination of specific Raman spectroscopy and optical morphology determination within 3 hours enables early, patient-oriented diagnosis of nosocomial urinary tract infections. The identification of the pathogens and the corresponding resistogram allow an adequate therapy treatment and thus contribute to a considerable relief of the patients themselves as well as to a drastic reduction of occurring costs in the care sector.
To achieve the project goal, the companies Biophotonics Diagnostics GmbH, Jenoptik Optical Systems GmbH, Grintech GmbH and BiFlow Systems GmbH are working together with the non-university Leibniz Institute for Photonic Technologies and the University Hospital Jena. Together, a miniaturized, low-cost measurement unit with different modalities (sample cartridge for urine analysis, imaging unit and Raman spectroscopy system) combined with automated evaluation strategies is being researched. The subproject of Leibniz-IPHT focuses on the research of a miniaturized Raman spectroscopic detection unit as well as sample preparation techniques and their integration into a microfluidic cartridge concept. Verification and validation of the researched modules will be carried out in cooperation with all partners.

The project is funded by the BMBF under the number 13GW0432E and co-financed by the project management organization VDI Düsseldorf in Berlin.

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