XLMA fibers based on Yb-doped bulk silica possess an excellent refractive index and doping level homogeneity [1]. To achieve the highest optical-to-optical efficiency and long-term operation without degradation we simulated the effect of the brightness conversion factor of different core dopant compositions of such XLMA fibers. We also investigated the beam quality of a multi-kW single XLMA fiber laser system and its long-term stability. The current state-of-the-art XLMA single fiber laser has 5 kW maximum output power and a degradation rate of about 0.5 % / 500 h at 4 kW measured over a period of 1700 h. Several application tests demonstrate the excellent performance of the XLMA fiber laser.