A brief review of new fiber microsphere geometries is presented. Simple microspheres working as Fabry–Perot cavities are interrogated in reflection and in transmission. Two microspheres were also spliced together, and subjected to different physical parameters. These structures are an alternative solution for load measurement and, when read in transmission, it is also possible to apply strain. Moreover, the structure is capable of being used under extreme ambient temperatures up to900 _C. Random signal in cleaved microspheres was demonstrated with the possibility of using it for random laser or sensing applications. All this work was developed at the Centre for Applied Photonics, INESC TEC.